Read the original sources for the topics below. Each description identifies the information supported by that source. These independent publications do not endorse or evaluate Seattle Trim Clinic.
How prescription weight-management medications work, individual eligibility, potential side effects, provider follow-up, and the role of nutrition and physical activity.
Dual GIP/GLP-1 receptor action, weight reduction and gastrointestinal adverse events in the placebo-controlled SURMOUNT-1 trial in adults without diabetes.
Compounded drugs are not FDA-approved; dosing, refrigeration during shipping, fraudulent products, and obtaining prescriptions through licensed professionals and state-licensed pharmacies.
Jastreboff AM, et al. New England Journal of Medicine. 2022.
Research published in the New England Journal of Medicine reported greater average weight reduction with tirzepatide than with placebo in the studied population, with gastrointestinal adverse events most common. The trial did not compare food-noise relief with semaglutide or study this clinic’s care.
Evidence limits: These sources do not establish an exact onset of food-noise relief, elimination of food-related thoughts, or tirzepatide’s superiority for food-noise relief. Clinical research on approved products does not establish equivalence of compounded formulations.
Compounded drugs are not FDA-approved. The FDA does not review compounded drugs for safety, effectiveness or quality before marketing. Compounded drugs should only be used when a patient's medical needs cannot be met by an FDA-approved drug.
Educational information is general, not individualized medical advice. Prescription treatment requires evaluation by a licensed provider. Eligibility, medication choice and dosing depend on individual circumstances.
Trim Clinic Network began with South Florida Trim Clinic. Through telehealth, Seattle Trim Clinic connects eligible patients with independent licensed medical providers for personalized care. Those providers evaluate patients and make treatment and prescribing decisions. No membership fees ever. Prescription treatment is available only where legally and clinically appropriate.